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Pravastatin, sold under the brand name Pravachol among others, is a statin medication, used for preventing cardiovascular disease in those at high risk and treating abnormal lipids. It should be used together with diet changes, exercise, and weight loss. [3] Dosage Modifications Coadministration with other drugs . Bile acid sequestrant: Administer atorvastatin/ezetimibe ≥2 hr before or ≥4 hr after administering bile acid sequestrant; Cyclosporine, tipranavir plus ritonavir, gemfibrozil: Avoid coadministration with atorvastatin (increased risk of rhabdomyolysis) Pravachol (pravastatin sodium) Tablets. This supplemental new drug application proposes changes in the format of the Pravachol package insert in response to the Physician’s Labeling Rule (PLR).
At 2 years, doses of pravastatin in patients available for follow-up were as follows: 10 mg, n = 1; 20 mg, n = 4; 40 mg, n = 2; 50 mg, n = 4; 60 mg, n = 3. Rosuvastatin Atorvastatin Pitavastatin Simvastatin Lovastatin Pravastatin Fluvastatin High-Intensity (lowers LDL-C ≥ 50%) 63 40 mg ($196) The dosage consisted of 10 mg of pravastatin daily during the 6-month trial. Over that period, in the pravastatin group, plasma levels of total cholesterol and LDL-cholesterol significantly (P <.01) dropped (-20% and -25%, respectively) compared to the placebo group. Pravastatin sodium is administered orally once daily preferably in the evening with or without food. Hypercholesterolaemia: The recommended dose range is 10 - 40 mg once daily. Pravastatin doesn't upset the stomach, so you can take it with or without food. Swallow pravastatin tablets whole with a glass of water.
Methods and results: We compared the efficacy of 10 mg of pravastatin and 10 mg of lovastatin in a randomized, crossover design trial among 30 patients with hypercholesterolemia. The proper dosage of pravastatin will vary between patients.
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(Canada) impairment.7,12. The recommended starting dose of pravastatin is 20 mg daily, taken with or without food in a single dose at bedtime. Your doctor will do blood tests to tell how 26 Mar 2015 Starting dosage: 10 mg PO qd.
Pharmacokinetics and pharmacodynamics of pravastatin in
10 mars 2004 — Comparison of the efficacy and safety of rosuvastatin versus atorvastatin, simvastatin, and pravastatin across doses. American Journal of The dose of atorvastatin in patients with homozygous familial lipid lowering with atorvastatin 80 mg and standard degree of lipid lowering with pravastatin. 4 aug. 2009 — Näst vanligaste statin var atorvastatin med drygt 100 000 (14 procent), medan 23 000 behandlades med pravastatin och 20 000 med av O Wiklund — Fluvastatin < Pravastatin < Simvastatin < Atorvastatin < Rosuvastatin. Relation mellan LDL-reduktion och dos för olika statiner. Adapterat från (8).
Reduction. HMG-CoA Reductase Inhibitor. Rosuvastatin. Atorvastatin. Pitavastatin. Simvastatin.
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At 2 years, doses of pravastatin in patients available for follow-up were as follows: 10 mg, n = 1; 20 mg, n = 4; 40 mg, n = 2; 50 mg, n = 4; 60 mg, n = 3. Rosuvastatin Atorvastatin Pitavastatin Simvastatin Lovastatin Pravastatin Fluvastatin High-Intensity (lowers LDL-C ≥ 50%) 63 40 mg ($196) The dosage consisted of 10 mg of pravastatin daily during the 6-month trial. Over that period, in the pravastatin group, plasma levels of total cholesterol and LDL-cholesterol significantly (P <.01) dropped (-20% and -25%, respectively) compared to the placebo group. Pravastatin sodium is administered orally once daily preferably in the evening with or without food.
PRAVACHOL can be administered orally as a single dose at any time of the day, with or without food. Use an initial dose of 1 mg in patients with GFR <60 mL/min/1.73 m2 and in hemodialysis patients; max dose 2 mg.6 NA Pravastatin (Pravachol, generics) 10 to 20 mg Use an initial dose of 10 mg in patients with a history of significant renal or liver (Canada) impairment.7,12 40 to 80 mg Use an initial dose of 10 mg in patients
Pravastatin doesn't upset the stomach, so you can take it with or without food. Swallow pravastatin tablets whole with a glass of water. In adults, the usual dose is 10mg to 40mg once a day.
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The dose range of pravastatin is 10-80 mg daily. The usual starting dose in adults is 40 mg once daily. The maximum dose is 80 mg per day. Dosage adjustment may be needed based on renal function, race, or drug interactions.
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10–40 mg daily, dose to be taken at night, dose to be adjusted at intervals of at least 4 weeks.
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Peter H Jones, MD. In the second phase of the study, we assessed the effects of a persistent reduction in cholesterol synthesis induced by increasing doses of pravastatin (20 mg Get information on Pravastatin tablets including uses, dosage details, medication side-effects and drug interaction facts from Cleveland Clinic's health library.
Uses: -In hypercholesterolemic patients without clinically evident coronary heart disease 2020-11-10 · Pravastatin doses are based on age, and are lower in children and teenagers. People taking this medicine during childhood or adolescence may need a different dose as adults.